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Nutrition ScienceCitation: Estruch R, et al. "Primary Prevention of Cardiovascular Disease with a Mediterranean Diet." New England Journal of Medicine, 2018.

The Mediterranean Diet's Measured Effect on Heart Disease Risk

What Happened

In the PREDIMED randomized controlled trial, high-cardiovascular-risk adults assigned to a Mediterranean diet supplemented with extra-virgin olive oil or mixed nuts had roughly a 30% lower rate of major cardiovascular events than those on a lower-fat control diet, over about five years.

Informational content based on peer-reviewed research and major health authority guidelines — not medical advice.

Why It Matters

PREDIMED is a randomized controlled trial, not an observational study of people who happened to already eat this way — that's what makes the 30% event-rate reduction one of the strongest results in dietary cardiology.

Randomized, not observational — and the fat sources were the point, not an afterthought.

FET's Takeaway

Supplementing with actual olive oil or nuts, not a low-fat control, is the detail that matters for formulation — this trial specifically validates unsaturated fat sources as part of the pattern, not just 'eat more vegetables.'

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